Flow Chemistry through Mechanochemical Synthesis Green chemistry Fully scalable Novel, patented technology FLOW CHEMISTRY In Flow Chemistry, chemical processes are taking place in a continuously flowing stream contrary to batch production. This offers several compelling advantages that can be highly beneficial in various industries. The main advantages are: Better mass and heat transfer Faster reactions Increased quality (conversion, yield and selectivity) Broad scalability Higher sustainability Improved safety due to smaller reaction volume MECHANO CHEMISTRY Mechanochemical reactions are understood to be “chemical transformations initiated or sustained by mechanical force”.1 It is considered as major technology to achieve the United Nations Goals for Sustainable Development (Agenda 2030). The main advantages are: Possibility of solvent-free reactions Better mixing of primary materials Excellent surface renewal of the reactants Higher productivity Energy savings Cost savings Reactions can take place at lower temperatures (1) Do, Jean-Louis & Friščić, Tomislav. Mechanochemistry: A Force of Synthesis. ACS Central Science 2017, 3, 1, 13–19. 2 / 12 THE SOLUTION WAB MECHANOCHEMICAL REACTORS Benefits of mechanochemical reactors with bead mill technology: Highest turbulences due to fast rotational speed up to 6’000 rpm Residence time independent from energy input High and very fast conversion, outstanding yield and selectivity Small reaction chamber with an exceptional surface to volume ratio Processing of dry, liquid, liquid assisted and viscous products Excellent surface renewal of the reactants trough bead mill technology Mechanical forces such as shock, pressure, shear, friction, impact and torsion apply Environmentally friendly by using  less resources  less solvents and generating less waste  less energy consumption  less space requirements  high level of automation Existing scale up from milligrams to tons Energy input through mechanochemistry and additionally with inductive heating device OUTSTANDING MECHANOCHEMISTRY A mechanochemical reactor with 0.5 litre reaction volume filled with 0.8 mm diameter beads contains more than 800’000 beads. The high rotational speed of the accelerators speed-up the beads and create billions of impacts where shock, pressure, shear, friction, impact and torsion apply. These impacts enhance the chemical reaction and create a constant renewal of the surface of the reactants. The high turbulences lead to an excellent mixing, exceptional homogeneity and therefore fast conversion, outstanding yield and selectivity. The residence time is settable and independent from the energy input. This allows the process to be conducted at the optimum operating point. Mechanical effects on molecules PRESSURE FRICTION SHOCK IMPACT SHEAR TORSION 3 / 12